The Last Dose update in GTA Online brings the Los Santos Drug Wars storyline to its thrilling climax through five action-packed narrative missions. Players must assist Dax and the Fooligans as they uncover corporate conspiracies and rescue kidnapped crew members from high-tech adversaries. Completing this series requires tactical preparation, heavy firepower, and smart driving strategies across Los Santos.
Starting the Last Dose Storyline
Before launching into these final missions, you must complete all six First Dose missions given by Dax at The Freakshop. Once the prerequisite content is cleared, wait for a phone call from Dax while exploring free mode. Accepting his call activates the yellow quest marker outside your headquarters, allowing you to begin the campaign.
Infiltration and Rescue Tactics
Early missions focus on tracking down leads and gathering intelligence on Dr. Friedlander's illicit pharmaceutical operation. During missions like FriedMind, equip heavy armor and carry a high-capacity assault rifle to clear tight indoor corridors efficiently. Always search designated rooms thoroughly for keycards and clues needed to breach basement holding areas.
Handling Heavy Combat and Vehicle Escorts
Mid-tier assignments throw swarms of armed goons and attack helicopters directly at your position. Utilizing weapons like the railgun or rocket launcher allows you to disable enemy choppers before they overwhelm your team. Stock up on snacks via your interaction menu to keep your health fully restored during intense shootouts.
Completing the Final Showdown and Rewards
The finale demands careful driving and defensive play as you escape hostile forces while protecting valuable cargo. Lose your wanted level by diving into subterranean railway tunnels near the city center before returning to safety. Successfully finishing all five missions rewards you with substantial cash payouts and unlocks Dr. Friedlander's personal supercar for free.
